Charleston is well covered for veterinary care, including genuine 24/7 emergency hospitals: the Charleston Veterinary Referral Center (CVRC) and BluePearl Pet Hospital in nearby Mount Pleasant both run around-the-clock emergency and specialty care with no referral needed, and Bees Ferry Veterinary Hospital offers urgent care to the west of the city. For routine visits, vaccinations or a check-up during a stay, plenty of day practices serve the peninsula and the suburbs. Save an emergency number before you arrive and call ahead so the team is ready for you.
Hampton Inn Charleston / Historic District
★★★ 8.6
Hyatt House Charleston / Historic District
★★★ 8.7
The Ryder Hotel
★★★★ 8.8
Verified pet policies, live Booking.com prices from €180/night.
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3163 W Montague Ave, North Charleston, SC 29418
A round-the-clock emergency and specialty animal hospital serving the Charleston area, open 24/7/365 with no referral required. It handles everything from urgent injuries and overnight emergencies to specialist care, making it the reassuring first call for a serious problem during your stay.
💡 Program the number into your phone on arrival, and call ahead so the emergency team is expecting you.
985 Johnnie Dodds Blvd, Mount Pleasant, SC 29464
A 24-hour emergency and specialty hospital just across the Cooper River in Mount Pleasant, handy if you are staying on the Isle of Palms or Sullivan's Island. No appointment is needed for emergencies, though calling ahead helps the team prepare for your arrival.
💡 This is the closest 24/7 option to the Sullivan's Island and Isle of Palms beaches, so note it if you are staying out there.
3422 Bees Ferry Rd, Charleston, SC 29414
A full-service veterinary hospital west of the Ashley River offering general care and urgent-care hours for accidents and sudden illness. A practical option for a same-day problem that is not a full-blown overnight emergency, and easily reached by car from the peninsula.
💡 Call ahead to confirm urgent-care availability, as hours can vary by day.
Our top-rated pet-friendly hotels, handpicked and verified.
Hampton Inn Charleston / Historic District
★★★ · 8.6/10
€180/night
Hyatt House Charleston / Historic District
★★★ · 8.7/10
€210/night
The Ryder Hotel
★★★★ · 8.8/10
€240/night